Benzenemethanamine, Α-Methyl-4-Nitro-, (Αs)-

Benzenemethanamine, Α-Methyl-4-Nitro-, (Αs)- - Names and Identifiers

Name	(S)-4-Nitro-α-methylbenzylamine
Synonyms	Nitrosolve S-O-NITRO-A-METHYLBENZYLAMINE S-O-Nitro-A-Methylbenzylamine (S)-4-Nitro-α-methylbenzylamine (S)-A-METHYL-4-NITROBENZYLAMINE (S)-A-Methyl-4-Nitrobenzylamine (S)-1-(4-NITROPHENYL)-ETHYLAMINE (1S)-1-(4-Nitrophenyl)Ethanamine (S)-1-(4-Nitrophenyl)-Ethylamine (S)-P-Nitro-Alpha-Methylbenzylamine (S)-4-NITRO-ALPHA-METHYLBENZYLAMINE (S)-p-Nitro-alpha-methylbenzylamine (S)-ALPHA-METHYL-4-NITROBENZYLAMINE (S)-4-Nitro-Alpha-Methylbenzylamine (S)-4-nitro-α-MethylbenzeneMethanaMine Benzenemethanamine, Α-Methyl-4-Nitro-, (Αs)-
CAS	4187-53-5
InChI	InChI=1/C8H10N2O2/c1-6(9)7-2-4-8(5-3-7)10(11)12/h2-6H,9H2,1H3/t6-/m0/s1

Benzenemethanamine, Α-Methyl-4-Nitro-, (Αs)- - Physico-chemical Properties

Molecular Formula	C8H10N2O2
Molar Mass	166.18
Density	1.199±0.06 g/cm3(Predicted)
Boling Point	120-121 °C(Press: 1 Torr)
Flash Point	128.4°C
Vapor Presure	0.00229mmHg at 25°C
pKa	8.31±0.10(Predicted)
Storage Condition	2-8°C
Refractive Index	1.576

Benzenemethanamine, Α-Methyl-4-Nitro-, (Αs)- - Introduction

(S)-is an organic compound with the chemical formula C8H9NO2. It is a colorless to pale yellow solid with a weak ammonia odor.

The compound is commonly used as a chiral reagent in organic synthesis. It can be used to synthesize compounds with chiral structures, especially drugs and biologically active molecules. It can also be used as a ligand for chiral catalysts for asymmetric synthesis reactions.

The method of preparing (S)-is relatively simple. One commonly used method is by the ortho-selective nitration and methylation of benzaldehyde. The specific steps include reacting benzaldehyde with sodium nitrite under the catalysis of sulfuric acid to obtain the corresponding nitrate ester of aldehyde. Then, the resulting nitrate ester is reduced to an amino compound, followed by a methylation reaction to obtain (S)-phosphonate.

Regarding the safety information of (S)-, it is an irritating substance. Care should be taken to avoid skin contact and inhalation during operation. At the same time, the operation should be carried out in a well-ventilated area and appropriate protective equipment, such as gloves and protective glasses, should be worn. Keep away from ignition and oxidizing agents during storage and handling. In the event of an accident, appropriate first aid and treatment measures should be taken immediately, and relevant advice should be consulted by the doctor.

Last Update：2024-04-09 21:54:55